Dr. Megan Wright

Assistant Professor of Biology
wrightm@arcadia.edu

Dr. Wright received her B.S. in Biomedical Sciences from Drexel University (2002) and her Ph.D. in Neuroscience from Drexel University College of Medicine (2007). She completed her postdoctoral fellowship in the lab of Dr. Ahmet Hoke in the Neurology Department at Johns Hopkins School of Medicine before joining the faculty at Arcadia University in the fall of 2010. Dr. Wright also holds an adjunct faculty appointment in the Neurology Department at Johns Hopkins University.

Dr. Wright teaches in the General Biology sequence (BI-101, 102), Neurobiology (BI-335), and Research Methods (BI-242). Her previous teaching experiences include courses in Human Anatomy, Human Physiology and Medical Neuroscience.

Research Interests

Dr. Wright’s general research interests are related to how peripheral axons and Schwann cells (the glial cells of the peripheral nervous system) communicate following injury, during development and in association with certain disease states. Using a variety of approaches including standard biochemical and molecular assays, in vitro models of axon-Schwann cell interactions, and in vivo rodent models of axonal regeneration, Dr. Wright studies the basic biology of Schwann cells and how these cells contribute to functional recovery following injury.

Representative Publications

  • AC Lepore, C Tolmie, J O’Donnell, MC Wright, C Dejea, B Rauck, A Hoke, AR Ignagni, RP Onders and NJ Maragakis, Peripheral Hyperstimulation Alters Site of Disease Onset and Course in SOD1G93A Rats. Neurobiology of Disease. 2010 Sep;39(3):252-64.
  • MC Wright, S Potluri, X Wang, E Dentcheva, D Gautam, A Tessler, J Wess, and YJ Son. Distinct muscarinic acetylcholine receptor subtypes contribute to stability and growth, but not compensatory plasticity, of neuromuscular synapses. The Journal of Neuroscience. 2009 Nov 25;29(47):14942-55.
  • MC Wright, WJ Cho, YJ Son. Distinct patterns of motor nerve terminal sprouting induced by ciliary neurotrophic factor vs. botulinum toxin. Journal of Comparative Neurology. 2007; Sep 1;504(1):1-16.
  • MC Wright, YJ Son. Ciliary neurotrophic factor is not required for terminal sprouting and compensatory reinnervation of neuromuscular synapses: re-evaluation of CNTF null mice. Experimental Neurology 2007;Jun;205(2):437-48.

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